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gscreend

gscreend

Statistical test for pooled CRISPR screens

Input data

Three files, organized as follows:

my_project
|-- gRNAs.tsv
|-- matrix.tsv
`-- samples.tsv

Output files

  • results.tsv: A list of genes with associated p-values, and log-fold changes

Parameter settings

  • direction — Direction of the screening experiment; possible values: “negative” (default), or “positive”

References

Please cite:

Imkeller et. al. Genome Biology 2020 Bioconductor gscreend package

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